Endocrine Abstracts

We have previously shown that Low T3 syndrome is associated with serum markers, radiologic and clinical scores of COVID-19 severity and it can be considered as a novel biomarker of the severity of the disease (Endocrine Abstracts 2020, 70 AEP1091). With the aim to analyze the mechanisms that are at the basis of this condition as well as the pathways involved, we applied an integrative approach of multi-omics data. We performed: i) multiplex cytokine assay, using the B...

Low T3 syndrome is a frequent finding in patients with critical illness, particularly in those admitted to intensive care units. It is generally considered an adaptive state of thyroid hormone (TH) economy, but many evidences indicate that it may represent a negative prognostic factor too. The prevalence and clinical relevance of the Low T3 syndrome in coronavirus infections has not been evaluated yet. We have measured thyroid hormone levels and analyzed anamnestic, epidemiolo...